IPoster: Decreased Peripapillary Capillary Density Corresponding to AION-related NFL, GCC and Visual Field Loss Using OCT Angiography

Introduction: Optical coherence tomography angiography (OCTA) is an emerging non-invasive imaging technology that allows in vivo visualization of the retinal and choroidal vasculatures, including the peripapillary capillary network. Over the past couple of years, the use of OCTA has provided insights into structural and functional vascular characteristics of various retinal and optic nerve disorders including ischemic optic neuropathies.

Case Report: We present a case of chronic non-arteritic anterior ischemic optic neuropathy (NA-AION) that showed sectoral decreased peripapillary capillary density on OCTA, which is in agreement with findings reported by multiple studies. The correlation of the OCTA with the nerve fiber layer (NFL), ganglion cell complex (GCC), and visual field loss will be discussed, as well as the significance of this correlation in terms of eliciting the underlying process.

Discussion: Optic neuropathies are a heterogeneous group of optic nerve disorders that require different management within different timelines, but yet many have similar ophthalmoscopic presentation, usually as optic disc edema or atrophy. The characterization of these various disorders using OCTA could provide a tool that would facilitate their differential diagnosis, allowing for prompt and accurate management of the condition. Furthermore, more insights into the ischemic process and loss of peripapillary capillaries in relation to NFL and visual field loss may shed light into the underlying pathophysiology, opening doors to new treatment modalities in the future.